Trial intelligence / Profile preview

Neratinib after trastuzumab in early HER2-positive breast cancer

2008-007345-31Phase 3Completed

Sponsor
Puma Biotechnology, Inc.
Start
Jun 2009
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in breast cancer and breast adenocarcinoma comparing Neratinib with Placebo (2 arms). Primary endpoint: Disease-free survival. Started Jun 2009; status: completed.

02

Drugs

neratinib
03

Conditions

breast cancerbreast adenocarcinoma

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