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Givinostat plus hydroxyurea in JAK2V617F-positive polycythemia vera resistant to hydroxyurea
2009-010982-22Phase 2Completed
- Sponsor
- Italfarmaco
- Start
- May 2009
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 2, open-label, single-arm trial of givinostat and hydroxyurea in polycythemia vera (PV), sponsored by Italfarmaco. Primary endpoint: Overall response rate at week 12. Started May 2009; status: completed.
02
Drugs
givinostathydroxyurea
03
Conditions
polycythemia vera (PV)
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