Trial intelligence / Profile preview

Randomized phase 2 trial of clofarabine plus standard induction chemotherapy in adults with previously untreated AML or high-risk MDS (RAEB)

2009-011613-24Phase 2Completed

Sponsor
HOVON
Start
Jul 2009
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised trial of clofarabine in acute myeloid leukemia (AML) and myelodysplastic syndrome with excess blasts (MDS-EB) (2 arms), sponsored by HOVON. Primary endpoint: Clinical efficacy of clofarabine in combination with induction cycles I and II. Started Jul 2009; status: completed.

02

Drugs

clofarabine
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome with excess blasts (MDS-EB)

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