Trial intelligence / Profile preview

Bosutinib plus capecitabine in advanced solid tumors and HER2-negative metastatic breast cancer

2009-011878-15Phase 2Completed

Sponsor
Wyeth
Start
Jul 2009
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of bosutinib and capecitabine in breast cancer, pancreatic cancer (PC), colorectal cancer (CRC) and 3 more, sponsored by Wyeth. Primary endpoints: Overall response rate, Safety and tolerability and 1 more. Started Jul 2009; status: completed.

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Drugs

bosutinibcapecitabine
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Conditions

breast cancerpancreatic cancer (PC)colorectal cancer (CRC)cholangiocarcinoma (CCA)glioblastoma (GBM)

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