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Therapeutic effectiveness of N-acetylcysteine and ascorbic acid in alkaptonuria-ochronosis
2009-012707-26Phase 2Terminated
- Sponsor
- Azienda Ospedaliera Universitaria Senese
- Start
- May 2009
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 2, single-arm trial of acetylcysteine in alkaptonuria (AKU) and ochronosis, sponsored by Azienda Ospedaliera Universitaria Senese. Primary endpoints: Primary: Effect of N-acetylcysteine on homogentisic acid levels and Primary: Inhibition of homogentisic acid oxidation and polymerization. Started May 2009; status: terminated.
02
Drugs
acetylcysteine
03
Conditions
alkaptonuria (AKU)ochronosis
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