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Pilot trial of noninvasive assessment of methotrexate hepatotoxicity in pharmacokinetically guided therapy of psoriasis
2009-015403-95Phase 4Completed
- Sponsor
- Fakultní nemocnice Hradec Králové
- Start
- Oct 2009
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 4, open-label trial of methotrexate in psoriasis (3 arms), sponsored by Fakultní nemocnice Hradec Králové. Primary endpoint: Change in noninvasive bioindicators of hepatotoxicity. Started Oct 2009; status: completed.
02
Drugs
methotrexate
03
Conditions
psoriasis
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