Trial intelligence / Profile preview

Phase II high-dose therapy with peripheral blood stem cell support in elderly patients with relapsed or refractory aggressive non-Hodgkin lymphoma

2009-015974-36Phase 2Completed

Sponsor
Gruppo Italiano Studio Linfomi
Start
Oct 2009
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of rituximab, dexamethasone, cisplatin, cytarabine, etoposide and 1 more in non-Hodgkin lymphoma (NHL), diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL) and 3 more, sponsored by Gruppo Italiano Studio Linfomi. Primary endpoints: 1-year event-free survival and Treatment-related mortality. Started Oct 2009; status: completed.

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Drugs

rituximabdexamethasonecisplatincytarabineetoposide
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Conditions

non-Hodgkin lymphoma (NHL)diffuse large B-cell lymphoma (DLBCL)follicular lymphoma (FL)mantle cell lymphoma (MCL)peripheral T-cell lymphoma (PTCL)

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