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Open-label Phase I/II Study of MEK Inhibitor GSK1120212 in Relapsed or Refractory Leukemias

2009-017376-25Phase 2Completed

Sponsor
GSK
Start
Feb 2011
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of trametinib in leukemia and acute myeloid leukemia (AML), sponsored by GSK. Primary endpoints: Safety and tolerability (Phase I component), Pharmacokinetics (Phase I/II) and 2 more. Started Feb 2011; status: completed.

02

Drugs

trametinib
03

Conditions

leukemiaacute myeloid leukemia (AML)

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