Trial intelligence / Profile preview

Aerosolized ALN-RSV01 in Lung Transplant Patients with RSV Infection

2009-017487-16Phase 2Completed

Sponsor
Alnylam Pharmaceuticals
Start
Dec 2009
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in respiratory syncytial virus disease (RSV) and Bronchiolitis Obliterans Syndrome (BOS) comparing ALN-RSV01 plus standard of care with Placebo plus standard of care (2 arms). Primary endpoint: Incidence of new or progressive bronchiolitis obliterans syndrome at Day 180. Started Dec 2009; status: completed.

02

Drugs

asvasiran
03

Conditions

respiratory syncytial virus disease (RSV)Bronchiolitis Obliterans Syndrome (BOS)

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