Trial intelligence / Profile preview

Phase I/IIa malaria sporozoite challenge study of AdCh63/MVA AMA1, MSP1, and ME-TRAP vaccines

2010-018341-56Phase 2Completed

Sponsor
University of Oxford
Start
Mar 2010
Modality
Prophylactic Vaccines → Vaccines & Immunotherapeutics, DNA Vaccines → Plasmid DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, open-label trial of adch63 ama1, MVA AMA1 vaccine, AdCh63 MSP1, mva msp1 vaccine, ChAd63 ME-TRAP and 1 more in malaria (4 arms), sponsored by University of Oxford. Primary endpoints: Protective efficacy against malaria infection and Time to parasitaemia. Started Mar 2010; status: completed.

02

Drugs

adch63 ama1MVA AMA1 vaccineAdCh63 MSP1mva msp1 vaccineChAd63 ME-TRAP
03

Conditions

malaria

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