Trial intelligence / Profile preview

Phase 2 trial of E10030 plus Lucentis versus Lucentis alone in neovascular age-related macular degeneration

2010-018741-65Phase 2Completed

Sponsor
IVERIC bio
Start
Mar 2010
Modality
Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics, RNA Aptamers → RNA Therapeutics → Nucleic Acid Therapeutics, DNA Aptamers → DNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in exudative macular degeneration, subfoveal choroidal neovascularization (CNV) and age-related macular degeneration (AMD) comparing E10030 + Lucentis with Lucentis monotherapy (2 arms). Primary endpoint: Mean change in visual acuity from baseline at Week 24. Started Mar 2010; status: completed.

02

Drugs

pegpleranibranibizumab
03

Conditions

exudative macular degenerationsubfoveal choroidal neovascularization (CNV)age-related macular degeneration (AMD)

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