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Hygiene protocol plus metronidazole added to antibiotic therapy for bisphosphonate-associated osteonecrosis of the jaw
2010-019060-37Phase 2Completed
- Sponsor
- Sant'Orsola-Malpighi University Hospital
- Start
- Jul 2010
- Modality
- Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 2, open-label trial of metronidazole, amoxicillin + clavulanate and ciprofloxacin in medication-related osteonecrosis of the jaw (MRONJ) and Osteomyelitis of the jaw (OM) (2 arms), sponsored by Sant'Orsola-Malpighi University Hospital. Primary endpoint: Primary efficacy endpoint. Started Jul 2010; status: completed.
02
Drugs
metronidazoleamoxicillin + clavulanateciprofloxacin
03
Conditions
medication-related osteonecrosis of the jaw (MRONJ)Osteomyelitis of the jaw (OM)
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