Trial intelligence / Profile preview

Phase II study of sequential T-DM1 after anthracycline-based chemotherapy in early HER2-positive breast cancer

2010-019752-50Phase 2Completed

Sponsor
Roche
Start
Jul 2010
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of trastuzumab emtansine in breast cancer, sponsored by Roche. Primary endpoint: Cardiac event rate within 12 weeks after starting T-DM1. Started Jul 2010; status: completed.

02

Drugs

trastuzumab emtansine
03

Conditions

breast cancer

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