Trial intelligence / Profile preview

Asfotase alfa in infants and young children with hypophosphatasia

2010-019850-42Phase 2Completed

Sponsor
Alexion Pharmaceuticals
Start
Oct 2010
Modality
Replacement Enzymes → Therapeutic Enzymes → Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of asfotase alfa in hypophosphatasia (HPP), sponsored by Alexion Pharmaceuticals. Primary endpoint: Effect of asfotase alfa treatment on skeletal manifestations of hypophosphatasia using Radiographic Global Impression of Change. Started Oct 2010; status: completed.

02

Drugs

asfotase alfa
03

Conditions

hypophosphatasia (HPP)

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