Trial intelligence / Profile preview

Neoadjuvant CAPOX followed by CRS+HIPEC for peritoneal carcinomatosis of colorectal origin

2010-020787-37Phase 2Active

Sponsor
University Medical Center Groningen
Start
Nov 2011
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of capecitabine, oxaliplatin and mitomycin c in peritoneal carcinomatosis (PC) and colorectal cancer (CRC), sponsored by University Medical Center Groningen. Primary endpoint: 30-day or in-hospital mortality following CRS+HIPEC after neoadjuvant chemotherapy. Started Nov 2011; status: active.

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Drugs

capecitabineoxaliplatinmitomycin c
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Conditions

peritoneal carcinomatosis (PC)colorectal cancer (CRC)

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