Trial intelligence / Profile preview

Phase II neoadjuvant lapatinib + oxaliplatin + capecitabine in HER2-positive gastric or gastroesophageal adenocarcinoma

2010-021118-47Phase 2Terminated

Sponsor
Fundación de Investigación HM Hospitales
Start
Jul 2010
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of lapatinib, oxaliplatin and capecitabine in gastric adenocarcinoma, gastroesophageal junction adenocarcinoma and esophageal adenocarcinoma (EAC), sponsored by Fundación de Investigación HM Hospitales. Primary endpoint: Pathologic complete response rate. Started Jul 2010; status: terminated.

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Drugs

lapatiniboxaliplatincapecitabine
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Conditions

gastric adenocarcinomagastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)

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