Trial intelligence / Profile preview

AML 18 Pilot Trial of AC220, plerixafor, or ganetespib with chemotherapy in older patients with AML or high-risk MDS

2010-021444-18Phase 2Completed

Sponsor
Cardiff University
Start
Oct 2010
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of quizartinib, plerixafor, ganetespib and clofarabine in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) (3 arms), sponsored by Cardiff University. Primary endpoints: Feasibility of combining investigational agent with chemotherapy and Toxicity. Started Oct 2010; status: completed.

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Drugs

quizartinibplerixaforganetespibclofarabine
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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