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Phase II single-arm study of methotrexate, pegfilgrastim, oxaliplatin, paclitaxel, and actinomycin D in relapsed poor-prognosis germ cell tumour

2010-022795-31Phase 2Completed

Sponsor
Barts Health NHS Trust
Start
Jun 2011
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of methotrexate, pegfilgrastim, oxaliplatin, paclitaxel and actinomycin D in germ cell tumor (GCT), sponsored by Barts Health NHS Trust. Primary endpoint: Complete response and negative marker partial response. Started Jun 2011; status: completed.

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Drugs

methotrexatepegfilgrastimoxaliplatinpaclitaxelactinomycin D
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Conditions

germ cell tumor (GCT)

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