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Probiotics vs co-trimoxazole for prevention of spontaneous bacterial peritonitis in cirrhosis with ascites
2010-022886-92Phase 4Terminated
- Sponsor
- Nottingham University Hospitals
- Start
- Feb 2011
- Modality
- Small Molecules, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Countries
- 1
01
Overview
Phase 4, randomised trial in Cirrhosis, ascites, primary peritonitis and 3 more comparing VSL#3 probiotics with Co-trimoxazole prophylaxis (2 arms). Primary endpoints: Overall liver-related mortality and Liver-related morbidity. Started Feb 2011; status: terminated.
02
Drugs
VSL#3trimethoprim + sulfamethoxazole
03
Conditions
Cirrhosisascitesprimary peritonitishepatic encephalopathy (HE)Variceal bleeding
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