Trial intelligence / Profile preview

Trabectedin + PLD versus carboplatin + PLD in partially platinum-sensitive relapsed ovarian cancer

2010-022949-17Phase 3Completed

Sponsor
Mario Negri Institute for Pharmacological Research
Start
Nov 2010
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised trial in ovarian cancer, fallopian tube cancer (PFTC) and primary peritoneal cancer (PPC) comparing Trabectedin + pegylated liposomal doxorubicin with Carboplatin + pegylated liposomal doxorubicin (2 arms). Primary endpoint: Overall survival. Started Nov 2010; status: completed.

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Drugs

trabectedindoxorubicincarboplatin
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Conditions

ovarian cancerfallopian tube cancer (PFTC)primary peritoneal cancer (PPC)

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