Trial intelligence / Profile preview

High volume haemodiafiltration in severe sepsis: pharmacokinetics of doripenem and piperacillin-tazobactam and inflammatory response

2011-000644-16Phase 4Completed

Sponsor
University of Tartu
Start
Mar 2011
Modality
Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label trial of doripenem, piperacillin and tazobactam in sepsis, septic shock and acute kidney failure (AKF) (2 arms), sponsored by University of Tartu. Primary endpoint: Pharmacokinetic parameters of doripenem and piperacillin-tazobactam during high volume haemodiafiltration. Started Mar 2011; status: completed.

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Drugs

doripenempiperacillintazobactam
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Conditions

sepsisseptic shockacute kidney failure (AKF)

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