Trial intelligence / Profile preview

FDG-PET/CT early response assessment during neoadjuvant chemotherapy for esophageal and esophagogastric junction adenocarcinoma

2011-001856-12Phase 4Completed

Sponsor
Motol University Hospital
Start
Jul 2011
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of cisplatin, epirubicin, fluorouracil and capecitabine in esophageal adenocarcinoma (EAC) and gastroesophageal junction adenocarcinoma, sponsored by Motol University Hospital. Primary endpoint: Threshold decrease in FDG-PET/CT metabolic parameters at day 14. Started Jul 2011; status: completed.

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Drugs

cisplatinepirubicinfluorouracilcapecitabine
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Conditions

esophageal adenocarcinoma (EAC)gastroesophageal junction adenocarcinoma

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