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TH-302 plus doxorubicin versus doxorubicin in advanced soft tissue sarcoma

2011-003145-17Phase 3Completed

Sponsor
Threshold Pharmaceuticals
Start
Dec 2011
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in soft tissue sarcoma (STS) comparing TH-302 + doxorubicin with doxorubicin alone (2 arms). Primary endpoint: Overall survival. Started Dec 2011; status: completed.

02

Drugs

evofosfamidedoxorubicin
03

Conditions

soft tissue sarcoma (STS)

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