Trial intelligence / Profile preview

Tivozanib + mFOLFOX6 versus bevacizumab + mFOLFOX6 in metastatic colorectal cancer

2011-003502-24Phase 2Completed

Sponsor
Astellas Pharma
Start
Dec 2011
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of tivozanib, bevacizumab, fluorouracil, folinic acid and oxaliplatin in colorectal cancer (CRC) (2 arms), sponsored by Astellas Pharma. Primary endpoint: Progression-free survival. Started Dec 2011; status: completed.

02

Drugs

tivozanibbevacizumabfluorouracilfolinic acidoxaliplatin
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Conditions

colorectal cancer (CRC)

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