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TREMERA
2011-004017-17Phase 4Completed
- Sponsor
- University of Leeds
- Start
- Jan 2013
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 4, randomised, open-label trial in rheumatoid arthritis (RA) comparing Tocilizumab + methotrexate with Tocilizumab monotherapy (2 arms). Primary endpoint: Change in expression of JAK 1-3 and related signaling proteins. Started Jan 2013; status: completed.
02
Drugs
tocilizumabmethotrexate
03
Conditions
rheumatoid arthritis (RA)
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