Trial intelligence / Profile preview

Phase 2 study of REGN727 in autosomal dominant hypercholesterolemia with PCSK9 gain-of-function mutations

2011-004308-39Phase 2Completed

Sponsor
Regeneron Pharmaceuticals
Start
Feb 2012
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of alirocumab in familial hypercholesterolemia (FH) (2 arms), sponsored by Regeneron Pharmaceuticals. Primary endpoint: Primary: percent change in direct serum LDL cholesterol. Started Feb 2012; status: completed.

02

Drugs

alirocumab
03

Conditions

familial hypercholesterolemia (FH)

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