Trial intelligence / Profile preview

GSK2118436 drug-drug interaction and pharmacokinetics study in BRAF-mutant solid tumors

2011-004436-61Phase 2Completed

Sponsor
GSK
Start
Mar 2012
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of dabrafenib + trametinib in Nonhematologic neoplasms and cutaneous malignancy (4 arms), sponsored by GSK. Primary endpoint: S-warfarin pharmacokinetics with and without dabrafenib. Started Mar 2012; status: completed.

02

Drugs

dabrafenib + trametinib
03

Conditions

Nonhematologic neoplasmscutaneous malignancy

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