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Early rheumatoid arthritis: active conventional therapy vs three biologic treatments and de-escalation strategies
2011-004720-35Phase 4Active
- Sponsor
- Karolinska Institutet
- Start
- Dec 2011
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
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Overview
Phase 4, randomised, single-blind trial of methotrexate and leflunomide in rheumatoid arthritis (RA) (4 arms), sponsored by Karolinska Institutet. Primary endpoint: CDAI remission at week 24. Started Dec 2011; status: active.
02
Drugs
methotrexateleflunomide
03
Conditions
rheumatoid arthritis (RA)
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