Trial intelligence / Profile preview

Tocilizumab plus methotrexate tapering versus stable methotrexate in severe active rheumatoid arthritis

2011-005260-20Phase 4Terminated

Sponsor
Roche
Start
May 2012
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 4, randomised trial of tocilizumab and methotrexate in rheumatoid arthritis (RA) (2 arms), sponsored by Roche. Primary endpoint: Maintenance of EULAR response from week 24 to week 56. Started May 2012; status: terminated.

02

Drugs

tocilizumabmethotrexate
03

Conditions

rheumatoid arthritis (RA)

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