Trial intelligence / Profile preview

Ceftazidime-avibactam versus doripenem for complicated urinary tract infection

2011-005722-21Phase 3Completed

Sponsor
AstraZeneca
Start
Apr 2012
Modality
Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in complicated urinary tract infection (cUTI) and acute pyelonephritis comparing Ceftazidime-avibactam arm with Doripenem arm (2 arms). Primary endpoints: Symptomatic resolution of UTI-specific symptoms at Day 5 and Microbiological response in the mMITT set. Started Apr 2012; status: completed.

02

Drugs

ceftazidime + avibactamdoripenem
03

Conditions

complicated urinary tract infection (cUTI)acute pyelonephritis

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