Trial intelligence / Profile preview

Dabrafenib + trametinib versus vemurafenib in BRAF V600E/K mutation-positive advanced cutaneous melanoma

2011-006088-23Phase 3Completed

Sponsor
Novartis
Start
Apr 2012
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in cutaneous melanoma (CM) and melanoma comparing dabrafenib + trametinib with vemurafenib (2 arms). Primary endpoint: overall survival. Started Apr 2012; status: completed.

02

Drugs

dabrafenib + trametinibtrametinibvemurafenib
03

Conditions

cutaneous melanoma (CM)melanoma

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