Trial intelligence / Profile preview

Ceftazidime-avibactam versus best available therapy for ceftazidime-resistant Gram-negative infections

2012-000726-21Phase 3Completed

Sponsor
AstraZeneca
Start
Jun 2012
Modality
Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial of ceftazidime + avibactam in complicated urinary tract infection (cUTI), Intra-abdominal infection (IAI) and Gram-negative bacterial infection (2 arms), sponsored by AstraZeneca. Primary endpoint: Clinical cure at test of cure in mMITT population. Started Jun 2012; status: completed.

02

Drugs

ceftazidime + avibactam
03

Conditions

complicated urinary tract infection (cUTI)Intra-abdominal infection (IAI)Gram-negative bacterial infection

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