Trial intelligence / Profile preview

Pilot trial assessing tolerability and effect of SYL1001 in patients with ocular pain

2012-001177-93Phase 2Completed

Sponsor
Sylentis
Start
Jul 2012
Modality
Vaccine mRNA → mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, single-arm trial of tivanisiran in dry eye syndrome (DED) and Ocular pain is not a disease; it is a symptom. The canonical disease entity most closely related to persistent, unexplained ocular pain is "ocular neuropathic pain" or "neuropathic ocular pain", sponsored by Sylentis. Primary endpoints: Analgesic effect on ocular pain and Ocular tolerability. Started Jul 2012; status: completed.

02

Drugs

tivanisiran
03

Conditions

dry eye syndrome (DED)Ocular pain is not a disease; it is a symptom. The canonical disease entity most closely related to persistent, unexplained ocular pain is "ocular neuropathic pain" or "neuropathic ocular pain".

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