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Double-blind trial of anastrozole (Arimidex) to delay epiphyseal fusion and increase height potential in adolescent males with growth hormone deficiency

2012-001183-30Phase 2

Sponsor
Nemours Children's Health
Start
Mar 2012
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial in growth hormone deficiency (GHD) and hypopituitarism comparing Arimidex + growth hormone with Placebo + growth hormone (2 arms). Primary endpoint: Change in predicted adult height at 24 months.

02

Drugs

anastrozole
03

Conditions

growth hormone deficiency (GHD)hypopituitarism

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