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Pharmacodynamics of doxapram with opioids (doxapram-101)
2012-001849-41Phase 4Active
- Sponsor
- Leiden University Medical Center
- Start
- May 2012
- Modality
- Small Molecules
- Countries
- 1
01
Overview
Phase 4, randomised trial in acute respiratory decompensation, opioid-induced respiratory depression (OIRD), atelectasis and 3 more comparing Dopram + Rapifen with Placebo + Rapifen (2 arms). Primary endpoint: Clinical utility of respiratory stimulants under opioid-induced respiratory depression and hypercapnia. Started May 2012; status: active.
02
Drugs
doxapram
03
Conditions
acute respiratory decompensationopioid-induced respiratory depression (OIRD)atelectasiscentral sleep apnea (CSA)apnea of prematurity (AOP)
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