Trial intelligence / Profile preview

Phase IIa open-label study of TMC647055 + simeprevir with ritonavir, with or without GSK2336805 and with or without ribavirin, in chronic genotype 1 hepatitis C

2012-002555-42Phase 2Completed

Sponsor
Janssen Pharmaceutical
Start
Jun 2012
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of TMC-647055, simeprevir, GSK2336805, ritonavir and ribavirin in hepatitis C virus infection (4 arms), sponsored by Janssen Pharmaceutical. Primary endpoint: Sustained virologic response 12 weeks after end of treatment. Started Jun 2012; status: completed.

02

Drugs

TMC-647055simeprevirGSK2336805ritonavirribavirin
03

Conditions

hepatitis C virus infection

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