Trial intelligence / Profile preview

Phase II randomized trial of MK-5172 + MK-8742 with or without ribavirin in treatment-naive chronic hepatitis C genotype 1

2012-003354-89Phase 2Terminated

Sponsor
Merck & Co.
Start
Dec 2012
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised trial of grazoprevir, verubecestat and ribavirin in hepatitis C virus infection (2 arms), sponsored by Merck & Co. Primary endpoint: Sustained virologic response at 12 weeks. Started Dec 2012; status: terminated.

02

Drugs

grazoprevirverubecestatribavirin
03

Conditions

hepatitis C virus infection

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