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Effect of naloxone and methylnaltrexone on oesophageal sensitivity in healthy volunteers
2012-003409-86Phase 4Completed
- Sponsor
- KU Leuven
- Start
- Aug 2012
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
- Countries
- 1
01
Overview
Phase 4, randomised, double-blind trial in esophageal hypersensitivity comparing Naloxone, Methylnaltrexone and Placebo (3 arms). Primary endpoint: Altered oesophageal sensitivity after naloxone or methylnaltrexone vs placebo. Started Aug 2012; status: completed.
02
Drugs
naloxonemethylnaltrexone
03
Conditions
esophageal hypersensitivity
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