Trial intelligence / Profile preview

DESTINY trial of tyrosine kinase inhibitor de-escalation and stopping in chronic myeloid leukemia

2012-004025-24Phase 2Completed

Sponsor
University of Liverpool
Start
Jun 2013
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of imatinib, dasatinib and nilotinib in chronic myelogenous leukemia (CML) (2 cohorts), sponsored by University of Liverpool. Primary endpoint: Loss of major molecular response. Started Jun 2013; status: completed.

02

Drugs

imatinibdasatinibnilotinib
03

Conditions

chronic myelogenous leukemia (CML)

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