Trial intelligence / Profile preview

Randomised double-blind phase II trial of Tocovid SupraBio plus pentoxifylline for chronic gastrointestinal adverse effects after pelvic radiotherapy

2012-004211-31Phase 2Completed

Sponsor
Royal Marsden NHS Foundation Trust
Start
Jun 2014
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, double-blind trial of tocovid and pentoxifylline in Radiation-induced gastrointestinal syndrome (RIGS), Radiation-Induced Injury and pelvic malignancies (2 arms), sponsored by Royal Marsden NHS Foundation Trust. Primary endpoint: Change at 12 months in the bowel disease subset of the Modified IBDQ Quality of Life questionnaire. Started Jun 2014; status: completed.

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Drugs

tocovidpentoxifylline
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Conditions

Radiation-induced gastrointestinal syndrome (RIGS)Radiation-Induced Injurypelvic malignancies

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