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Perioperative drug dosing and tissue pharmacokinetics in obese and non-obese surgical patients
2012-004383-22Phase 3Completed
- Sponsor
- Leipzig University
- Start
- Jan 2013
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, open-label trial of linezolid, meropenem, acetaminophen, Metamizole sodium, tigecycline and 2 more in surgical site infection (SSI) and postoperative pain (4 arms), sponsored by Leipzig University. Primary endpoint: Interstitial fluid antibiotic exposure. Started Jan 2013; status: completed.
02
Drugs
linezolidmeropenemacetaminophenMetamizole sodiumtigecycline
03
Conditions
surgical site infection (SSI)postoperative pain
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