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Phase II biomarker study of upfront versus delayed dabrafenib + trametinib in BRAF-mutant unresectable or metastatic melanoma

2012-004577-12Phase 2Completed

Sponsor
GSK
Start
Feb 2015
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial of dabrafenib + trametinib and trametinib in melanoma (3 arms), sponsored by GSK. Primary endpoint: Percentage change of ERK phosphorylation score from baseline. Started Feb 2015; status: completed.

02

Drugs

dabrafenib + trametinibtrametinib
03

Conditions

melanoma

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