Trial intelligence / Profile preview

Telaprevir plus pegylated interferon/ribavirin versus pegylated interferon/ribavirin for acute genotype 1 hepatitis C in HIV-1 coinfected adults

2012-005525-75Phase 3Completed

Sponsor
St Stephen's AIDS Trust
Start
Apr 2013
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in hepatitis C virus infection and Human immunodeficiency virus infection type 1 comparing Incivo + pegylated interferon + ribavirin with Pegylated interferon + ribavirin (2 arms). Primary endpoint: Sustained virologic response at 24 weeks. Started Apr 2013; status: completed.

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Drugs

telaprevirpegylated interferon alpharibavirin
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Conditions

hepatitis C virus infectionHuman immunodeficiency virus infection type 1

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