Trial intelligence / Profile preview

Tacrolimus-Rituximab versus steroids plus cyclophosphamide in primary membranous nephropathy

2013-000226-55Phase 3Active

Sponsor
Fundación Renal Española
Start
Jun 2013
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, RNA-Targeting Small Molecules → Nucleic Acid-Directed Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in idiopathic membranous glomerulonephritis (IMG) comparing Sequential tacrolimus followed by rituximab with Cyclical corticosteroids plus cyclophosphamide (2 arms). Primary endpoint: Complete or partial remission at 24 months. Started Jun 2013; status: active.

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Drugs

tacrolimusrituximabcyclophosphamidecorticosteroids
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Conditions

idiopathic membranous glomerulonephritis (IMG)

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