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Phase IIb biomarker discovery trial of carboplatin + cyclophosphamide versus paclitaxel with or without atezolizumab in advanced triple-negative breast cancer

2013-001484-23Phase 2Active

Sponsor
Borstkanker Onderzoek Groep
Start
Apr 2013
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of atezolizumab, paclitaxel, carboplatin and cyclophosphamide in triple-negative breast cancer (TNBC) and breast cancer (4 arms), sponsored by Borstkanker Onderzoek Groep. Primary endpoint: BRCA-like biomarker prediction of differential progression-free survival. Started Apr 2013; status: active.

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Drugs

atezolizumabpaclitaxelcarboplatincyclophosphamide
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Conditions

triple-negative breast cancer (TNBC)breast cancer

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