Trial intelligence / Profile preview

Phase 2 Open-Label Study of ALN-TTRSC in Transthyretin Cardiac Amyloidosis

2013-002856-33Phase 2Completed

Sponsor
Alnylam Pharmaceuticals
Start
Sep 2013
Modality
Gene Therapies, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 2, open-label, single-arm trial of revusiran in amyloidotic transthyretin cardiomyopathy (ATTR-CM) and hereditary transthyretin amyloidosis (hATTR), sponsored by Alnylam Pharmaceuticals. Primary endpoint: Safety and tolerability of multiple doses of ALN-TTRSC. Started Sep 2013; status: completed.

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Drugs

revusiran
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Conditions

amyloidotic transthyretin cardiomyopathy (ATTR-CM)hereditary transthyretin amyloidosis (hATTR)

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