Trial intelligence / Profile preview

SYLTAG phase II study of SYL040012 (bamosiran) vs timolol in open-angle glaucoma or ocular hypertension

2013-002947-27Phase 2Completed

Sponsor
Sylentis
Start
Jun 2014
Modality
Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 2, randomised, single-blind trial of bamosiran in open-angle glaucoma (OAG) and ocular hypertension (2 arms), sponsored by Sylentis. Primary endpoint: Change in mean diurnal intraocular pressure at Day 28. Started Jun 2014; status: completed.

02

Drugs

bamosiran
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Conditions

open-angle glaucoma (OAG)ocular hypertension

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