Trial intelligence / Profile preview

Treosulfan pharmacokinetics in paediatric allogeneic HSCT

2013-003257-20Phase 4Completed

Sponsor
Great Ormond Street Hospital
Start
Mar 2014
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of treosulfan in leukemia, Immunogenetic disorder, Congenital Metabolic Diseases and 2 more, sponsored by Great Ormond Street Hospital. Primary endpoints: Treosulfan Cmax, Treosulfan half-life (t1/2) and 1 more. Started Mar 2014; status: completed.

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Drugs

treosulfan
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Conditions

leukemiaImmunogenetic disorderCongenital Metabolic Diseasesautoimmune diseaseinflammatory bowel disease (IBD)

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