Trial intelligence / Profile preview

Alectinib versus crizotinib in treatment-naive ALK-positive advanced non-small cell lung cancer

2013-004133-33Phase 3Active

Sponsor
Roche
Start
Jun 2014
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Alectinib with Crizotinib (2 arms). Primary endpoint: Progression-free survival. Started Jun 2014; status: active.

02

Drugs

alectinibcrizotinib
03

Conditions

non-small cell lung cancer (NSCLC)

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