Trial intelligence / Profile preview

STOP-NUC trial: stopping nucleos(t)ide analogue therapy in HBeAg-negative chronic hepatitis B

2013-004882-15Phase 4Completed

Sponsor
Leipzig University
Start
May 2014
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, randomised trial of lamivudine, adefovir dipivoxil, telbivudine, entecavir and tenofovir in Chronic hepatitis B (CHB) (2 arms), sponsored by Leipzig University. Primary endpoint: Sustained HBsAg loss up to week 96. Started May 2014; status: completed.

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Drugs

lamivudineadefovir dipivoxiltelbivudineentecavirtenofovir
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Conditions

Chronic hepatitis B (CHB)

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